2-[N-甲基-N-(2-吡啶基)氨基]乙醇合成路线 （共 9 条）
反应条件
T=140°C; 0.333333 h; Sealed vesselNeat (no solvent);
参考文献
Gaonkar, Santosh L.; Shimizu, Hiroki
Tetrahedron, 2010 , vol. 66, # 18 p. 3314 - 3317
反应条件
potassium fluoride on basic alumina 0.25 h; microwave irradiation;
参考文献
Yang, De-Hong; Yang, Ben-Yong; Chen, Zhen-Chu; Chen, Song-Ying
Journal of Chemical Research, 2006 , # 9 p. 600 - 601
反应条件
potassium carbonate in dimethyl sulfoxide T=100°C; 4 h;
参考文献
Jawale, Dhanaji V.; Pratap, Umesh R.; Mane, Ramrao A.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 2 p. 924 - 928
反应条件
1: 1.) NaH / 1.) DMF, RT, 2.) DMF, RT, 18 h 2: 95 percent / piperidinium acetate / toluene / 2 h / Heating View Scheme
参考文献
Jawale, Dhanaji V.; Pratap, Umesh R.; Mane, Ramrao A.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 2 p. 924 - 928
反应条件
1: sodium hydride / N,N-dimethyl-formamide / 80 °C 2: piperidine / toluene / 2 h / 80 °C 3: iodine; magnesium / methanol / 3 h / Reflux View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 2 p. 924 - 928
反应条件
1: potassium carbonate / dimethyl sulfoxide / 4 h / 100 °C 2: iodine; magnesium / methanol / 3 h / Reflux View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 2 p. 924 - 928
反应条件
tetra(n-butyl)ammonium hydrogensulfate; potassium hydroxide in water; toluene T=85°C; 0.333333 h; Sealed vesselMicrowave irradiation;
参考文献
Gaonkar, Santosh L.; Shimizu, Hiroki
Tetrahedron, 2010 , vol. 66, # 18 p. 3314 - 3317
参考文献
Beecham Group p.l.c.
Patent: US5232925 A1, 1993 ;
反应条件
potassium tert-butylate in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; ethyl acetate
参考文献
Takasugi, Hisashi; Terasawa, Takeshi; Inoue, Yoshikazu; Nakamura, Hideko; Nagayoshi, Akira; Ohtake, Hiroaki; Furukawa, Yoshiro; Mikami, Masafumi; Hinoue, Kazumasa; Ohtsubo, Makoto
Patent: US2004/58903 A1, 2004 ;
