对甲基-N-甲基-N-甲氧基苯甲酰胺合成路线 （共 18 条）
反应条件
1: O,N-dimethyl-hydroxylamine hydrochloride With triethylamine in dichloromethane T=0°C; Inert atmosphere; 2: 4-methyl-benzoyl chloride in dichloromethane T=0 - 20°C; Inert atmosphere;
参考文献
Kishore Kumar; Chavarria, Gustavo E.; Charlton-Sevcik, Amanda K.; Arispe, Wara M.; MacDonough, Matthew T.; Strecker, Tracy E.; Chen, Shen-En; Siim, Bronwyn G.; Chaplin, David J.; Trawick, Mary Lynn; Pinney, Kevin G.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 4 p. 1415 - 1419
反应条件
1: 4-methyl-benzoic acid With N-ethyl-N,N-diisopropylamine; [bis(2-methoxyethyl)amino]-sulfur trifluoride in N,N-dimethyl-formamide T=0°C; 0.25 h; 2: N,O-dimethyl-hydroxylamine in N,N-dimethyl-formamide T=0 - 20°C; 4 h; Further stages.;
参考文献
Tunoori, Ashok Rao; White, Jonathan M.; Georg, Gunda I.
Organic Letters, 2000 , vol. 2, # 25 p. 4091 - 4093
反应条件
1: 4-methyl-benzoic acid With triethylamine; trichloromethyl chloroformate in dichloromethane T=0°C; 2: O,N-dimethyl-hydroxylamine hydrochloride in dichloromethane T=25°C; 1 h;
参考文献
Kim, Misoo; Lee, Hagyoung; Han, Ki-Jong; Kay, Kwang-Yol
Synthetic Communications, 2003 , vol. 33, # 23 p. 4013 - 4018
参考文献
Niu, Teng; Zhang, Weiming; Huang, Danfeng; Xu, Changming; Wang, Haifeng; Hu, Yulai
Organic Letters, 2009 , vol. 11, # 19 p. 4474 - 4477
反应条件
bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran T=60°C; 6 h;
参考文献
Murakami, Masahiro; Hoshino, Yujiro; Ito, Hajime; Ito, Yoshihiko
Chemistry Letters, 1998 , # 2 p. 163 - 164
反应条件
in tetrahydrofuran Inert atmosphereReflux;
参考文献
Phan, Diem H. T.; Kim, Byoungmoo; Dong, Vy M.
Journal of the American Chemical Society, 2009 , vol. 131, # 43 p. 15608 - 15609
反应条件
in methanol T=30°C; 3 h;
参考文献
Journal of Organic Chemistry, , vol. 68, # 5 p. 1810 - 1814
反应条件
pyridine in chloroform
参考文献
Tetrahedron Letters, , vol. 39, # 12 p. 1509 - 1512
反应条件
in tetrahydrofuran T=0°C; 0.25 h;
参考文献
Synthetic Communications, , vol. 29, # 8 p. 1249 - 1255
反应条件
1: SOCl2 2: Et3N View Scheme
参考文献
Synlett, , # 18 p. 2841 - 2846
