4-氯-N-甲氧基-N-甲基乙酰胺合成路线 （共 42 条）
反应条件
1.1: isopropylmagnesium chloride / tetrahydrofuran / 1 h / -20 °C
1.2: 3.5 h / -78 - 0 °C
2.1: hydrogen bromide; acetic acid / water / 36 h / 125 °C
View Scheme
参考文献
Debnath, Joy; Siricilla, Shajila; Wan, Bajoie; Crick, Dean C.; Lenaerts, Anne J.; Franzblau, Scott G.; Kurosu, Michio
Journal of Medicinal Chemistry, 2012 , vol. 55, # 8 p. 3739 - 3755
参考文献
Bhatt, Ulhas; Duffy, Bryan C.; Guzzo, Peter R.; Cheng, Leifeng; Elebring, Thomas
Synthetic Communications, 2007 , vol. 37, # 16 p. 2793 - 2806
