N-Fmoc-反式-4-羟基-L-脯氨酸甲酯合成路线 （共 5 条）
反应条件
sodium carbonate in 1,4-dioxane; water T=20°C; 48 h;
参考文献
Liu, Hongqiang; Pattabiraman, Vijaya R.; Vederas, John C.
Organic Letters, 2007 , vol. 9, # 21 p. 4211 - 4214
反应条件
sodium carbonate in tetrahydrofuran T=20°C; 18 h;
参考文献
Lewis, Ian; Bauer, Wilfried; Albert, Rainer; Chandramouli, Nagarajan; Pless, Janos; Weckbecker, Gisbert; Bruns, Christian
Journal of Medicinal Chemistry, 2003 , vol. 46, # 12 p. 2334 - 2344
反应条件
sodium hydrogencarbonate in water; acetone T=20°C; 3 h;
参考文献
Chemistry - A European Journal, , vol. 15, # 40 p. 10649 - 10657
反应条件
hydrogenchloride 4 h; Heating; Yield given;
参考文献
Journal of Fluorine Chemistry, , vol. 82, # 2 p. 125 - 130
反应条件
1.1: tetrahydrofuran / 3 h / 20 °C 2.1: 51.0 g / (dimethylamino)pyridine / tetrahydrofuran / 20 °C 3.1: aq. NaOH / dioxane 3.2: 71 percent / aq. sodium carbonate / tetrahydrofuran / 18 h / 20 °C View Scheme
参考文献
Lewis, Ian; Bauer, Wilfried; Albert, Rainer; Chandramouli, Nagarajan; Pless, Janos; Weckbecker, Gisbert; Bruns, Christian
Journal of Medicinal Chemistry, 2003 , vol. 46, # 12 p. 2334 - 2344
