4,4'-二溴-2,2'-双(三异丙基硅烷基)-5,5'-联噻唑合成路线 （共 4 条）
反应条件
1: With lithium diisopropyl amide in tetrahydrofuran; hexane
0.25 h; Inert atmosphereCooling with acetone-dry ice;
2: With copper dichloride in tetrahydrofuran; hexane
2 h;
参考文献
GEORGIA TECH RESEARCH CORPORATION; GETMANENKO, Yulia A.; MARDER, Seth; HWANG, Do Kyung; KIPPELEN, Bernard
Patent: WO2013/23109 A1, 2013 ;
Location in patent: Page/Page column 41; 42 ;
反应条件
1: 2,2'-dibromo-[5,5']bithiazolyl With lithium diisopropyl amide in tetrahydrofuran; hexane
T=-78°C; 0.5 h; Inert atmosphere;
2: triisopropylsilyl chloride in tetrahydrofuran; hexane
T=-78 - 20°C; Inert atmosphere;
参考文献
Al-Hashimi, Mohammed; Labram, John G.; Watkins, Scott; Motevalli, Majid; Anthopoulos, Thomas D.; Heeney, Martin
Organic Letters, 2010 , vol. 12, # 23 p. 5478 - 5481
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane
0.25 h; Inert atmosphereCooling with acetone-dry ice;
2: With bromine in tetrahydrofuran; hexane
Inert atmosphereCooling with acetone-dry ice; Further stages;
参考文献
Getmanenko, Yulia A.; Risko, Chad; Tongwa, Paul; Kim, Eung-Gun; Li, Hong; Sandhu, Bhupinder; Timofeeva, Tatiana; Bredas, Jean-Luc; Marder, Seth R.
Journal of Organic Chemistry, 2011 , vol. 76, # 8 p. 2660 - 2671
反应条件
1.1: n-butyllithium / diethyl ether; hexane / 0.5 h / 20 °C / Inert atmosphere; Cooling with acetone-dry ice
2.1: n-butyllithium / tetrahydrofuran; hexane / 0.25 h / Inert atmosphere; Cooling with acetone-dry ice
2.2: Inert atmosphere; Cooling with acetone-dry ice
View Scheme
参考文献
Getmanenko, Yulia A.; Risko, Chad; Tongwa, Paul; Kim, Eung-Gun; Li, Hong; Sandhu, Bhupinder; Timofeeva, Tatiana; Bredas, Jean-Luc; Marder, Seth R.
Journal of Organic Chemistry, 2011 , vol. 76, # 8 p. 2660 - 2671
