2-[(4-氯苯基)(4-哌啶基氧基)甲基]吡啶合成路线 （共 10 条）
反应条件
1: T=130°C; 5 h; Large scale; 2: With hydrogenchloride in water T=80°C; 15 h; Large scale;
参考文献
US2014/46068 A1, ;
Paragraph 0039; 0042; 0043; 0044; 0045; 0046; 0047 ;
反应条件
1: triethylamine / toluene / 1 h / 0 - 20 °C 2: N-ethyl-N,N-diisopropylamine / 3 h / 80 °C 3: sodium hydroxide / isopropyl alcohol / 12 h / |Reflux 4: 5 h / 20 °C 5: sodium hydroxide / dichloromethane / 0.17 h / 20 °C View Scheme
参考文献
Bulletin of the Korean Chemical Society, , vol. 34, # 2 p. 549 - 552
反应条件
1: sodium hydroxide / isopropyl alcohol / 12 h / |Reflux 2: 5 h / 20 °C 3: sodium hydroxide / dichloromethane / 0.17 h / 20 °C View Scheme
参考文献
Bulletin of the Korean Chemical Society, , vol. 34, # 2 p. 549 - 552
反应条件
1.1: triethylamine / dichloromethane / 1 h / -70 °C / |Large scale 1.2: 20 °C / |Large scale 2.1: 5 h / 130 °C / |Large scale 2.2: 15 h / 80 °C / |Large scale View Scheme
参考文献
Ube Industries, Ltd.
Patent: US4929618 A1, 1990 ;
参考文献
Ube Industries, Ltd.
Patent: US4929618 A1, 1990 ;
参考文献
Ube Industries, Ltd.
Patent: US4929618 A1, 1990 ;
参考文献
Ube Industries, Ltd.
Patent: US4929618 A1, 1990 ;
反应条件
1: sodium iodide; potassium carbonate / acetonitrile / 15 h / 80 °C / |Large scale 2: acetic acid / water 3: sodium hydroxide / ethanol / 15 h / 20 °C 4: acetonitrile / 15 h / 20 °C View Scheme
参考文献
EVERLIGHT USA, INC.; CHEN, Tsung-Ting; YANG, Hao-Cheng; CHOU, Tsai-Yung; YAO, Chi-Hsiang
Patent: US2014/46068 A1, 2014 ;
参考文献
Ube Industries, Ltd.
Patent: US4929618 A1, 1990 ;
