2-吡啶基[4-(三氟甲基)苯基]甲酮合成路线 （共 6 条）
反应条件
manganese(IV) oxide in dichloromethane 7 h;
参考文献
Hirayama, Tasuku; Ueda, Satoshi; Okada, Takahiro; Tsurue, Norihiko; Okuda, Kensuke; Nagasawa, Hideko
Chemistry - A European Journal, 2014 , vol. 20, # 14 p. 4156 - 4162
反应条件
pyridinium chlorochromate
参考文献
Tobisu; Chatani; Asaumi; Amako; Ie; Fukumoto; Murai
Journal of the American Chemical Society, 2000 , vol. 122, # 51 p. 12663 - 12674
反应条件
1: 1-trifluoromethyl-4-bromobenzene With magnesium in tetrahydrofuran Inert atmosphere; 2: 2-pyridine carbonitrile in tetrahydrofuran T=0°C; Inert atmosphere; 3: With hydrogenchloride; water in diethyl ether 0.5 h; Inert atmosphere;
参考文献
Tao, Xiaoming; Li, Wanfang; Ma, Xin; Li, Xiaoming; Fan, Weizheng; Xie, Xiaomin; Ayad, Tahar; Ratovelomanana-Vidal, Virginie; Zhang, Zhaoguo
Journal of Organic Chemistry, 2012 , vol. 77, # 1 p. 612 - 616
反应条件
1: 94 percent / 1.) BuLi / hexane; diethyl ether / 1.) -70 to -50 deg C, 10 min, 2.) -10 deg C 2: 62 percent / pyridinium dichromate / CH2Cl2 View Scheme
参考文献
Hirayama, Tasuku; Ueda, Satoshi; Okada, Takahiro; Tsurue, Norihiko; Okuda, Kensuke; Nagasawa, Hideko
Chemistry - A European Journal, 2014 , vol. 20, # 14 p. 4156 - 4162
反应条件
1: 94 percent / 1.) BuLi / hexane; diethyl ether / 1.) -70 to -50 deg C, 10 min, 2.) -10 deg C 2: 62 percent / pyridinium dichromate / CH2Cl2 View Scheme
参考文献
Buschauer, Armin
Archiv der Pharmazie (Weinheim, Germany), 1989 , vol. 322, p. 165 - 171
反应条件
1: 6 h / |Reflux; |Inert atmosphere 2: manganese(IV) oxide / dichloromethane / 7 h View Scheme
参考文献
Hirayama, Tasuku; Ueda, Satoshi; Okada, Takahiro; Tsurue, Norihiko; Okuda, Kensuke; Nagasawa, Hideko
Chemistry - A European Journal, 2014 , vol. 20, # 14 p. 4156 - 4162
