2-甲氧基-5-硝基烟酸甲酯合成路线 (共 4 条)
反应条件
ammonium nitrate; trifluoroacetic anhydride 2 h;
参考文献
Sarges; Goldstein; Welch; Swindell; Siegel; Beyer
Journal of Medicinal Chemistry, 1990 , vol. 33, # 7 p. 1859 - 1865
反应条件
1: 85 percent / SnCl2*2H2O / ethyl acetate / 0.33 h / Heating 2: 1.) 23percent H2SiF6, HOAc, butyl nitrite / 2.) xylene, 130 deg C, 15 min View Scheme
参考文献
Sarges; Goldstein; Welch; Swindell; Siegel; Beyer
Journal of Medicinal Chemistry, 1990 , vol. 33, # 7 p. 1859 - 1865
反应条件
hydrogen in methanol
参考文献
Merck and Co., Inc.
Patent: US5750549 A1, 1998 ;
US 5750549 A
反应条件
tin(ll) chloride in ethyl acetate 0.333333 h; Heating;
参考文献
Sarges; Goldstein; Welch; Swindell; Siegel; Beyer
Journal of Medicinal Chemistry, 1990 , vol. 33, # 7 p. 1859 - 1865