5-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)苯并[d]噁唑-2-胺合成路线 (共 3 条)
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate in 1,4-dioxane T=20 - 110°C; 2 h; Inert atmosphere;
参考文献
INTELLIKINE, LLC; REN, Pingda; MARTIN, Michael
Patent: WO2013/23184 A1, 2013 ;
Location in patent: Paragraph 00233; 00234 ;
WO 2013/023184 A1
反应条件
1: methanol / 15 h / 18 - 37 °C / |Large scale 2: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; potassium acetate / 1,4-dioxane / 18 - 103 °C / |Inert atmosphere; |Reflux; |Large scale View Scheme
参考文献
INTELLIKINE, LLC; REN, Pingda; MARTIN, Michael
Patent: WO2013/23184 A1, 2013 ;
WO 2013/023184 A1
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in 1,4-dioxane; water T=20 - 110°C; 3 h; Inert atmosphere;
参考文献
WO2013/23184 A1, ;
Paragraph 00237; 00238 ;
WO 2013/023184 A1