ammonia; sodium in 1,4-dioxane; methanol T=80°C; 2 h; Heating;

1: 1.) zinc bromide, lithium / 2.) tetrakis(triphenylphosphine)palladium / 1.) THF, 0 deg C, 2 h, ultrasonic activation; 2.) THF, room temperature, 3 h 2: sodium, ammonia / methanol; dioxane / 2 h / 80 °C / Heating View Scheme

1: 1.) zinc bromide, lithium / 2.) tetrakis(triphenylphosphine)palladium / 1.) THF, 0 deg C, 2 h, ultrasonic activation; 2.) THF, room temperature, 3 h 2: sodium, ammonia / methanol; dioxane / 2 h / 80 °C / Heating View Scheme