3-(2-溴乙酰基)吡咯烷-1-羧酸叔丁酯合成路线 （共 2 条）
反应条件
1: With chloro-trimethyl-silane; lithium hexamethyldisilazane in tetrahydrofuran T=-78 - 0°C; 2: With N-bromosuccinmide in tetrahydrofuran T=0°C; 0.5 h;
参考文献
MERCK SHARP andamp; DOHME CORP.; OGAWA, Anthony; OK, Hyun, O.; ONDEYKA, Debra; UJJAINWALLA, Feroze; VANDE BUNTE, Ellen
Patent: WO2010/77624 A1, 2010 ;
Location in patent: Page/Page column 52 ;
WO 2010/077624 A1
反应条件
sodium hydrogencarbonate in ethanol T=120°C; 0.25 h; Sealed tubeMicrowave irradiation;
参考文献
MERCK SHARP andamp; DOHME CORP.; OGAWA, Anthony; OK, Hyun, O.; ONDEYKA, Debra; UJJAINWALLA, Feroze; VANDE BUNTE, Ellen
Patent: WO2010/77624 A1, 2010 ;
Location in patent: Page/Page column 52 ;
WO 2010/077624 A1
