5-溴-2-[(甲基磺酰基)氨基]苯甲酸合成路线 （共 2 条）
反应条件
1: With water; sodium hydroxide in tetrahydrofuran T=20°C; 2: With hydrogenchloride in tetrahydrofuran; water
参考文献
GILEAD SCIENCES, INC.; BABAOGLU, Kerim; BOOJAMRA, Constantine, G.; EISENBERG, Eugene, J.; HUI, Hon Chung; MACKMAN, Richard, L.; PARRISH, Jay, P.; SANGI, Michael; SAUNDERS, Oliver, L.; SIEGEL, Dustin; SPERANDIO, David; YANG, Hai
Patent: WO2011/163518 A1, 2011 ;
Location in patent: Page/Page column 300 ;
WO 2011/163518 A1
反应条件
1: pyridine / dichloromethane / 20 °C 2: sodium hydroxide; water / tetrahydrofuran / 20 °C View Scheme
参考文献
GILEAD SCIENCES, INC.; BABAOGLU, Kerim; BOOJAMRA, Constantine, G.; EISENBERG, Eugene, J.; HUI, Hon Chung; MACKMAN, Richard, L.; PARRISH, Jay, P.; SANGI, Michael; SAUNDERS, Oliver, L.; SIEGEL, Dustin; SPERANDIO, David; YANG, Hai
Patent: WO2011/163518 A1, 2011 ;
WO 2011/163518 A1
