N-(3-羟基-4-甲氧基苄基)-N-[2-(4-羟基苯基)乙基]甲酰胺合成路线 （共 5 条）
反应条件
formic acid in 1,4-dioxane; N,N-dimethyl-formamide T=87 - 103°C; 4.5 h; Heating / reflux;
参考文献
Sanochemia Pharmazeutica
Patent: US6369238 B1, 2002 ;
Location in patent: Example 6 ;
反应条件
1: methanol / 1.) molecular sieves, r.t., overnight 2: sodium borohydride / methanol / 3 h / Ambient temperature 3: 80 percent / formic acid / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 25, # 6 p. 1809 - 1811
反应条件
1: methanol / 1.) molecular sieves, r.t., overnight 2: sodium borohydride / methanol / 3 h / Ambient temperature 3: 80 percent / formic acid / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 25, # 6 p. 1809 - 1811
反应条件
1: sodium borohydride / methanol / 3 h / Ambient temperature 2: 80 percent / formic acid / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 25, # 6 p. 1809 - 1811
反应条件
bromine in ethanol; 2-methoxy-ethanol T=-20°C; 0.75 h;
参考文献
Sanochemia Pharmazeutica
Patent: US6369238 B1, 2002 ;
Location in patent: Example 9 ;
