4-叠氮基-2,3,5,6-四氟苯甲酸甲酯合成路线 （共 18 条）
反应条件
sodium azide in water; acetone Substitution; 16 h; Heating;
参考文献
Journal of Organic Chemistry, , vol. 65, # 16 p. 4949 - 4953
反应条件
sodium azide in water; acetone T=70°C; 0.25 h; RefluxMicrowave irradiation;
参考文献
Journal of Fluorine Chemistry, , vol. 156, p. 164 - 169
反应条件
sodium azide; trifluoroacetic acid; sodium nitrite T=0°C; 2.66667 h;
参考文献
Journal of Physical Chemistry, , vol. 98, # 2 p. 412 - 419
反应条件
1: 96 percent / conc. H2SO4 / CCl4 / Heating 2: 87 percent / NaN3 / acetone; H2O / 8 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 55, # 11 p. 3640 - 3647
反应条件
1: 98 percent / aq. NaOH / methanol / 25 °C 2: 100 percent / PCl5 / diethyl ether / 1 h / 20 °C 3: sodium azide / acetone; H2O / 0.25 h / 0 °C 4: 88 percent / benzene / 7 h / 70 °C View Scheme
参考文献
Chehade, Kareem A. H.; Spielmann, H. Peter
Journal of Organic Chemistry, 2000 , vol. 65, # 16 p. 4949 - 4953
反应条件
sodium hydroxide in methanol; water T=25°C;
参考文献
Chehade, Kareem A. H.; Spielmann, H. Peter
Journal of Organic Chemistry, 2000 , vol. 65, # 16 p. 4949 - 4953
反应条件
1: 94 percent / LiOH*H2O / methanol; H2O / 23 h / 25 °C 2: 99 percent / DCC / tetrahydrofuran / 34 h / 25 °C View Scheme
参考文献
Kim, Jinkyu; Hong, Daewha; Jeong, Seungpyo; Kong, Bokyung; Kang, Sung Min; Kim, Yang-Gyun; Choi, Insung S.
Chemistry - An Asian Journal, 2011 , vol. 6, # 2 p. 363 - 366
反应条件
1: 98 percent / aq. NaOH / methanol / 25 °C 2: 100 percent / PCl5 / diethyl ether / 1 h / 20 °C 3: sodium azide / acetone; H2O / 0.25 h / 0 °C 4: 92 percent / benzene / 7 h / 70 °C 5: 86 percent / trifluoroacetic acid / CH2Cl2 / 0 - 20 °C View Scheme
参考文献
Chehade, Kareem A. H.; Spielmann, H. Peter
Journal of Organic Chemistry, 2000 , vol. 65, # 16 p. 4949 - 4953
反应条件
1: 98 percent / aq. NaOH / methanol / 25 °C 2: 100 percent / PCl5 / diethyl ether / 1 h / 20 °C View Scheme
参考文献
Keana, John F. W.; Cai, Sui Xiong
Journal of Organic Chemistry, 1990 , vol. 55, # 11 p. 3640 - 3647
反应条件
tin(ll) chloride in ethanol; ethyl acetate
0.0166667 h; Ambient temperature;
参考文献
Gee; Keana
Synthetic Communications, 1993 , vol. 23, # 3 p. 357 - 360
