4-叠氮基-2,3,5,6-四氟苯甲酸合成路线 （共 18 条）
反应条件
sodium hydroxide in methanol; water T=25°C;
参考文献
Chehade, Kareem A. H.; Spielmann, H. Peter
Journal of Organic Chemistry, 2000 , vol. 65, # 16 p. 4949 - 4953
反应条件
sodium peroxide in water T=50°C; 42 h;
参考文献
Keana, John F. W.; Cai, Sui Xiong
Journal of Organic Chemistry, 1990 , vol. 55, # 11 p. 3640 - 3647
反应条件
1: With sodium nitrite in trifluoroacetic acid 1 h; 2: With sodium azide in diethyl ether 2 h; Further stages.;
参考文献
Cismas, Crina; Gimisis, Thanasis
Tetrahedron Letters, 2008 , vol. 49, # 8 p. 1336 - 1339
反应条件
1: 96 percent / NaN3 / acetone; H2O / 16 h / Heating 2: 98 percent / aq. NaOH / methanol / 25 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 65, # 16 p. 4949 - 4953
反应条件
1: 18 percent / H2O2, (n-C4H9)4NHSO4, 20percent aq. NaOH / CH2Cl2 / 40 h / 25 °C 2: 64 percent / Na2O2 / H2O / 42 h / 50 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 55, # 11 p. 3640 - 3647
反应条件
1: 83 percent / NaN3 / acetone; H2O / 8 h / Heating 2: 64 percent / Na2O2 / H2O / 42 h / 50 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 55, # 11 p. 3640 - 3647
反应条件
1: 96 percent / conc. H2SO4 / CCl4 / Heating 2: 87 percent / NaN3 / acetone; H2O / 8 h / Heating 3: 98 percent / 20percent aq. NaOH / methanol; H2O / 25 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 55, # 11 p. 3640 - 3647
反应条件
1: 96 percent / TFA, NaNO2, NaN3 / 2.67 h / 0 °C 2: 94 percent / LiOH*H2O / methanol; H2O / 23 h / 25 °C View Scheme
参考文献
Journal of Physical Chemistry, , vol. 98, # 2 p. 412 - 419
反应条件
Title compound not separated from byproducts;
参考文献
Journal of Fluorine Chemistry, , vol. 126, # 5 p. 739 - 743
