4-叠氮基-2,3,5,6-四氟苯甲酸合成路线 （共 18 条）
反应条件
sodium L-ascorbate; copper(II) sulfate in tetrahydrofuran T=70°C; 22 h;
参考文献
Xia, Yi; Li, Wei; Qu, Fanqi; Fan, Zhijin; Liu, Xiufeng; Berro, Charles; Rauzy, Evelyne; Peng, Ling
Organic and Biomolecular Chemistry, 2007 , vol. 5, # 11 p. 1695 - 1701
反应条件
1: 100 percent / PCl5 / diethyl ether / 1 h / 20 °C 2: sodium azide / acetone; H2O / 0.25 h / 0 °C 3: 88 percent / benzene / 7 h / 70 °C View Scheme
参考文献
Chehade, Kareem A. H.; Spielmann, H. Peter
Journal of Organic Chemistry, 2000 , vol. 65, # 16 p. 4949 - 4953
反应条件
1: 100 percent / PCl5 / diethyl ether / 0.17 h 2: 48 percent / AlCl3, TiCl4 / CH2Cl2 / 24 h / 25 °C 3: 80 percent / BF3*SMe2 / CH2Cl2 / 13 h / 25 °C / in the dark View Scheme
参考文献
Pinney, Kevin G.; Katzenellenbogen, John A.
Journal of Organic Chemistry, 1991 , vol. 56, # 9 p. 3125 - 3133
反应条件
dicyclohexyl-carbodiimide in dichloromethane T=25°C;
参考文献
Marcinek, Andrzej; Platz, Matthew S.; Chan, Stephen Y.; Floresca, Rey; Rajagopalan, Krishnan; et al.
Journal of Physical Chemistry, 1994 , vol. 98, # 2 p. 412 - 419
反应条件
EDAC; sodium sulfate in dichloromethane
参考文献
THE STATE OF OREGON ACTING BY AND THROUGH STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND
Patent: US2010/28559 A1, 2010 ;
反应条件
1: 100 percent / PCl5 / diethyl ether / 1 h / 20 °C 2: sodium azide / acetone; H2O / 0.25 h / 0 °C 3: 92 percent / benzene / 7 h / 70 °C 4: 86 percent / trifluoroacetic acid / CH2Cl2 / 0 - 20 °C View Scheme
参考文献
Chehade, Kareem A. H.; Spielmann, H. Peter
Journal of Organic Chemistry, 2000 , vol. 65, # 16 p. 4949 - 4953
反应条件
phosphorus pentachloride in diethyl ether 0.166667 h;
参考文献
Chehade, Kareem A. H.; Spielmann, H. Peter
Journal of Organic Chemistry, 2000 , vol. 65, # 16 p. 4949 - 4953
反应条件
1: 41 percent / acetonitrile / 0.75 h
View Scheme
参考文献
Rajagopalan, Raghavan; Kuntz, Robert R.; Sharma, Uday; Volkert, Wynn A.; Pandurangi, Raghoottama S.
Journal of Organic Chemistry, 2002 , vol. 67, # 19 p. 6748 - 6757
