6-乙酰基-2-吡啶羧酸合成路线 （共 10 条）
反应条件
hydrogenchloride 2 h; Heating;
参考文献
Dalton Transactions, , # 10 p. 1006 - 1022
反应条件
dihydrogen peroxide in water
参考文献
Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, , vol. 38, # 4 p. 516 - 520
反应条件
1.1: n-butylithium / diethyl ether / 0.5 h / -60 °C 1.2: 57 percent / diethyl ether / -60 - 20 °C 2.1: 93 percent / HCl / 2 h / Heating View Scheme
参考文献
Dalton Transactions, , # 10 p. 1006 - 1022
反应条件
1.1: 89 percent / 4-toluenesulfonic acid monohydrate / toluene / 24 h / Heating 2.1: n-butylithium / diethyl ether / 0.5 h / -60 °C 2.2: 57 percent / diethyl ether / -60 - 20 °C 3.1: 93 percent / HCl / 2 h / Heating View Scheme
参考文献
Dalton Transactions, , # 10 p. 1006 - 1022
反应条件
1: 80 percent / p-toluene sulfonic acid / toluene / 4 h / Heating 2: 1.) Na, CH3OH / benzene / 1.) 1 h, reflux, 2.) 16 h, r.t. 3: 3.5 percent HCl / 1 h / Heating 4: 30percent H2O2 / H2O View Scheme
参考文献
Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, , vol. 38, # 4 p. 516 - 520
反应条件
hydrogenchloride; water T=37°C; 72 h;
参考文献
Synthetic Communications, , vol. 39, # 24 p. 4429 - 4440
反应条件
1: Br2 / acetic acid / 0.17 h / 110 °C 2: 4 h / Heating 3: 91.3 percent / aq. NaOH / ethanol / 4 h / Heating View Scheme
参考文献
Chihiro; Nagamoto; Takemura; Kitano; Komatsu; Sekiguchi; Tabusa; Mori; Tominaga; Yabuuchi
Journal of Medicinal Chemistry, 1995 , vol. 38, # 2 p. 353 - 358
参考文献
Yu, Kang-Kang; Li, Kun; Hou, Ji-Ting; Yu, Xiao-Qi
Tetrahedron Letters, 2013 , vol. 54, # 43 p. 5771 - 5774
反应条件
1: thionyl chloride 2: sodium tetrahydroborate / ethanol / 13 h / 0 - 20 °C / |Reflux 3: hydrogen bromide / 15 h / |Reflux View Scheme
参考文献
Yu, Kang-Kang; Li, Kun; Hou, Ji-Ting; Yu, Xiao-Qi
Tetrahedron Letters, 2013 , vol. 54, # 43 p. 5771 - 5774
反应条件
1: thionyl chloride 2: sodium tetrahydroborate / ethanol / 13 h / 0 - 20 °C / |Reflux View Scheme
参考文献
Yu, Kang-Kang; Li, Kun; Hou, Ji-Ting; Yu, Xiao-Qi
Tetrahedron Letters, 2013 , vol. 54, # 43 p. 5771 - 5774
