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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
1226467-43-1
合成路线
(共 8 条)
1226467-43-1
→
反应条件
6500-65-8
2-甲氧基苯并环庚-5-酮
反应条件
1: hydrogen / palladium 10 on activated carbon / ethanol / 12 h 2: methanesulfonic acid; phosphorous pentoxide / 12 h / Inert atmosphere View Scheme
参考文献
US2012/130129 A1, ;
1226467-43-1
→
反应条件
6500-64-7
5-(3-甲氧基苯基)戊酸
反应条件
hydrogen; palladium 10 on activated carbon in ethanol 12 h;
参考文献
BAYLOR UNIVERSITY
Patent: US2012/130129 A1, 2012 ;
Location in patent: Page/Page column 16 ;
1226467-43-1
→
反应条件
71089-18-4
+
71089-19-5
反应条件
1: hydrogen / palladium 10 on activated carbon / ethanol / 12 h 2: methanesulfonic acid; phosphorous pentoxide / 12 h / Inert atmosphere 3: nitric acid; acetic anhydride / acetic acid / 3 h / -78 °C View Scheme
参考文献
BAYLOR UNIVERSITY
Patent: US2012/130129 A1, 2012 ;
1226467-43-1
→
反应条件
71089-18-4
反应条件
1: palladium 10 on activated carbon; hydrogen / methanol / 24 h 2: phosphorous pentoxide; methanesulfonic acid / 12 h / |Inert atmosphere 3: acetic acid; acetic anhydride; nitric acid / -10 °C View Scheme
参考文献
Tanpure, Rajendra P.; George, Clinton S.; Sriram, Madhavi; Strecker, Tracy E.; Tidmore, Justin K.; Hamel, Ernest; Charlton-Sevcik, Amanda K.; Chaplin, David J.; Trawick, Mary Lynn; Pinney, Kevin G.
MedChemComm, 2012 , vol. 3, # 6 p. 720 - 724
1226467-43-1
→
反应条件
71089-18-4
+
71089-19-5
反应条件
1: hydrogen / palladium 10 on activated carbon / ethanol / 12 h 2: methanesulfonic acid; phosphorous pentoxide / 12 h / Inert atmosphere 3: nitric acid; acetic anhydride / acetic acid / 3 h / -78 °C View Scheme
参考文献
BAYLOR UNIVERSITY
Patent: US2012/130129 A1, 2012 ;
1226467-43-1
→
反应条件
71089-19-5
反应条件
1: palladium 10 on activated carbon; hydrogen / methanol / 24 h 2: phosphorous pentoxide; methanesulfonic acid / 12 h / |Inert atmosphere 3: acetic acid; acetic anhydride; nitric acid / -10 °C View Scheme
参考文献
Tanpure, Rajendra P.; George, Clinton S.; Sriram, Madhavi; Strecker, Tracy E.; Tidmore, Justin K.; Hamel, Ernest; Charlton-Sevcik, Amanda K.; Chaplin, David J.; Trawick, Mary Lynn; Pinney, Kevin G.
MedChemComm, 2012 , vol. 3, # 6 p. 720 - 724
1226467-43-1
→
反应条件
139909-01-6
+
80859-00-3
1,2,3,4-四氢-6-羟基-1-萘羧酸
反应条件
1: hydrogen; platinum on activated charcoal / methanol 2: methanesulfonic acid; phosphorous pentoxide 3: AlCl3, aluminium chloride / benzene / |Reflux 4: copper(ll) bromide / ethyl acetate; chloroform / |Reflux 5: silver(l) oxide / acetonitrile / 60 °C 6: acetonitrile-D3; water-d2 / |Photolysis View Scheme
参考文献
Kammath, Viju Balachandran; Solomek, Tomas; Ngoy, Bokolombe Pitchou; Heger, Dominik; Klan, Petr; Rubina, Marina; Givens, Richard S.
Journal of Organic Chemistry, 2013 , vol. 78, # 5 p. 1718 - 1729
1226467-43-1
→
反应条件
1382491-00-0
+
139909-01-6
+
80859-00-3
1,2,3,4-四氢-6-羟基-1-萘羧酸
反应条件
1: hydrogen; platinum on activated charcoal / methanol 2: methanesulfonic acid; phosphorous pentoxide 3: AlCl3, aluminium chloride / benzene / |Reflux 4: potassium carbonate / acetonitrile / 20 °C 5: potassium permanganate / benzene / |Reflux; |Dean-Stark 6: palladium 10 on activated carbon; hydrogen / ethyl acetate / 20 °C 7: acetonitrile-D3; water-d2 / |Photolysis View Scheme
参考文献
Kammath, Viju Balachandran; Solomek, Tomas; Ngoy, Bokolombe Pitchou; Heger, Dominik; Klan, Petr; Rubina, Marina; Givens, Richard S.
Journal of Organic Chemistry, 2013 , vol. 78, # 5 p. 1718 - 1729