3-硫代氨基甲酰吡咯烷-1-羧酸叔丁酯合成路线 （共 7 条）
反应条件
bis(trimethylsilyl)-sulfide; sodium methylate in 1,3-dimethyl-imidazolidin-2-one; methanol T=20°C;
参考文献
WO2006/97691 A1, ;
Page/Page column 23 ;
WO 2006/097691 A1
反应条件
Lawesson's reagent in benzene 2 h; Heating;
参考文献
MacLeod; Baker; Freedman; Patel; Merchant; Roe; Saunders
Journal of Medicinal Chemistry, 1990 , vol. 33, # 7 p. 2052 - 2059
反应条件
1: 73 percent / CH2Cl2 / 16 h / 20 °C 2: aq. NaOH / methanol / 0.25 h 3: Et3N / CH2Cl2 / 0 - 20 °C 4: NH3 / CH2Cl2 5: 45 percent / Lawesson's reagent / benzene / 2 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 7 p. 2052 - 2059
反应条件
1: 73 percent / CH2Cl2 / 16 h / 20 °C 2: aq. NaOH / methanol / 0.25 h 3: Et3N / CH2Cl2 / 0 - 20 °C 4: NH3 / CH2Cl2 5: 45 percent / Lawesson's reagent / benzene / 2 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 7 p. 2052 - 2059
反应条件
1: Et3N / CH2Cl2 / 0 - 20 °C 2: NH3 / CH2Cl2 3: 45 percent / Lawesson's reagent / benzene / 2 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 7 p. 2052 - 2059
反应条件
1: aq. NaOH / methanol / 0.25 h 2: Et3N / CH2Cl2 / 0 - 20 °C 3: NH3 / CH2Cl2 4: 45 percent / Lawesson's reagent / benzene / 2 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 7 p. 2052 - 2059
反应条件
manganese(IV) oxide in chloroform P=760.051 Torr; 0.25 h;
参考文献
Chemical Communications, , vol. 48, # 91 p. 11247 - 11249
