1,3-双(4-甲氧基苯基)脲合成路线 （共 75 条）
反应条件
T=20°C; Rate constant;
参考文献
Huenig et al.
Justus Liebigs Annalen der Chemie, 1953 , vol. 579, p. 87,88,89
反应条件
1: 83 percent / nitrosyl chloride / dimethylformamide / 2 h / 0 °C
2: 56 percent Spectr. / 1 N sodium hydroxide / ethanol / 0.08 h / Ambient temperature
View Scheme
参考文献
Miyahara; Kamiya; Nakadate
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 1 p. 41 - 44
反应条件
1H-imidazole; N,N-dimethyl-formamide in neat (no solvent)
T=150°C; 3 h;
参考文献
Neves Filho, Ricardo A. W.; Palm-Forster, Mieder A. T.; De Oliveira, Ronaldo N.
Synthetic Communications, 2013 , vol. 43, # 11 p. 1571 - 1576
反应条件
nitrosyl chloride in N,N-dimethyl-formamide
T=0°C; 2 h;
参考文献
Miyahara; Kamiya; Nakadate
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 1 p. 41 - 44
反应条件
1.1: water / 150 °C / |Green chemistry
2.1: triethylamine / dichloromethane / 0.17 h / |Inert atmosphere; |Cooling with ice
2.2: 25 °C / |Inert atmosphere; |Cooling with ice
View Scheme
参考文献
Medina-Ramos, Wilmarie; Mojica, Mike A.; Cope, Elizabeth D.; Hart, Ryan J.; Pollet, Pamela; Eckert, Charles A.; Liotta, Charles L.
Green Chemistry, 2014 , vol. 16, # 4 p. 2147 - 2155
