1: With Pearlman's catalist; hydrogen in methanol
T=20°C; P=760.051 Torr; 48 h;
2: With hydrogenchloride in methanol
参考文献
Davies, Stephen G.; Fletcher, Ai M.; Hughes, Deri G.; Lee, James A.; Price, Paul D.; Roberts, Paul M.; Russell, Angela J.; Smith, Andrew D.; Thomson, James E.; Williams, Oliver M.H.
Tetrahedron, 2011 , vol. 67, # 51 p. 9975 - 9992
1: With Pearlman's catalist; hydrogen in methanol
T=20°C; P=760.051 Torr; 48 h;
2: With hydrogenchloride in methanol
参考文献
Davies, Stephen G.; Hughes, Deri G.; Price, Paul D.; Roberts, Paul M.; Russell, Angela J.; Smith, Andrew D.; Thomson, James E.; Williams, Oliver M.H.
Synlett, 2010 , # 4 art. no. D34409ST, p. 567 - 570
Multi-step reaction with 5 steps 1.1: 1H-imidazole; iodine; triphenylphosphine / toluene; acetonitrile / 16 h / 65 °C2.1: silver tetrafluoroborate / acetonitrile / 16 h / 80 °C3.1: diisobutylaluminium hydride / tetrahydrofuran / 6 h / 0 - 20 °C / Inert atmosphere4.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.33 h / -78 °C4.2: -78 - 20 °C5.1: potassium tert-butylate / tetrahydrofuran / 0.5 h / 0 - 20 °C5.2: 16 h / 20 °C
参考文献
Davies, Stephen G.; Fletcher, Ai M.; Hughes, Deri G.; Lee, James A.; Price, Paul D.; Roberts, Paul M.; Russell, Angela J.; Smith, Andrew D.; Thomson, James E.; Williams, Oliver M.H. Tetrahedron, 2011 , vol. 67, # 51 p. 9975 - 9992
Multi-step reaction with 4 steps 1.1: silver tetrafluoroborate / acetonitrile / 16 h / 80 °C2.1: diisobutylaluminium hydride / tetrahydrofuran / 6 h / 0 - 20 °C / Inert atmosphere3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.33 h / -78 °C3.2: -78 - 20 °C4.1: potassium tert-butylate / tetrahydrofuran / 0.5 h / 0 - 20 °C4.2: 16 h / 20 °C
参考文献
Davies, Stephen G.; Fletcher, Ai M.; Hughes, Deri G.; Lee, James A.; Price, Paul D.; Roberts, Paul M.; Russell, Angela J.; Smith, Andrew D.; Thomson, James E.; Williams, Oliver M.H. Tetrahedron, 2011 , vol. 67, # 51 p. 9975 - 9992
Multi-step reaction with 5 steps 1.1: 1H-imidazole; iodine; triphenylphosphine / toluene; acetonitrile / 16 h / 65 °C2.1: silver tetrafluoroborate / 16 h / 80 °C3.1: diisobutylaluminium hydride / tetrahydrofuran / 6 h / 0 - 20 °C / Inert atmosphere4.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.33 h / -78 °C4.2: -78 - 20 °C5.1: potassium tert-butylate / tetrahydrofuran / 0.5 h / 0 - 20 °C5.2: 16 h / 20 °C
参考文献
Davies, Stephen G.; Fletcher, Ai M.; Hughes, Deri G.; Lee, James A.; Price, Paul D.; Roberts, Paul M.; Russell, Angela J.; Smith, Andrew D.; Thomson, James E.; Williams, Oliver M.H. Tetrahedron, 2011 , vol. 67, # 51 p. 9975 - 9992
Multi-step reaction with 4 steps 1.1: silver tetrafluoroborate / 16 h / 80 °C2.1: diisobutylaluminium hydride / tetrahydrofuran / 6 h / 0 - 20 °C / Inert atmosphere3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.33 h / -78 °C3.2: -78 - 20 °C4.1: potassium tert-butylate / tetrahydrofuran / 0.5 h / 0 - 20 °C4.2: 16 h / 20 °C
参考文献
Davies, Stephen G.; Fletcher, Ai M.; Hughes, Deri G.; Lee, James A.; Price, Paul D.; Roberts, Paul M.; Russell, Angela J.; Smith, Andrew D.; Thomson, James E.; Williams, Oliver M.H. Tetrahedron, 2011 , vol. 67, # 51 p. 9975 - 9992
