n-butyllithium; N,N,N',N,-tetramethylethylenediamine 1) THF, hexane, -70 deg C, 0.5 h, 2) THF, hexane, -40 deg C; Yield given. Multistep reaction;

1: 1) NaNH2, 2) NH4Cl / liq. NH3, Et2O 2: 1) BuLi, tetramethylethylenediamine (TMEDA), 2) TMEDA / 1) THF, hexane, -70 deg C, 0.5 h, 2) THF, hexane, -40 deg C View Scheme

Amberlyst 15 in tetrahydrofuran; water Ambient temperature;