3-氨基-1-苄基-1H-吡唑-4-甲腈合成路线 （共 5 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=70°C; 1.83333 h;
参考文献
WO2012/30924 A1, ;
Page/Page column 147 ;
WO 2012/030924 A1
反应条件
potassium carbonate in N,N-dimethyl-formamide T=100°C;
参考文献
Da Settimo, Federico; Primofiore, Giampaolo; La Motta, Concettina; Taliani, Sabrina; Simorini, Francesca; Marini, Anna Maria; Mugnaini, Laura; Lavecchia, Antonio; Novellino, Ettore; Tuscano, Daniela; Martini, Claudia
Journal of Medicinal Chemistry, 2005 , vol. 48, # 16 p. 5162 - 5174
反应条件
adogen 464; potassium carbonate in toluene Heating;
参考文献
Chakrabarti, Jiban K.; Hotten, Terrence M.; Pullar, Ian A.; Tye, Nicholas C.
Journal of Medicinal Chemistry, 1989 , vol. 32, # 12 p. 2573 - 2582
反应条件
sodium methylate 2 h;
参考文献
Tetrahedron Letters, , vol. 52, # 14 p. 1561 - 1565
反应条件
sulfuric acid
T=20°C; 2 h;
参考文献
AMBIT BIOSCIENCES CORPORATION; CHAO, Qi; HADD, Michael, J.; HOLLADAY, Mark, W.; ROWBOTTOM, Martin
Patent: WO2012/30924 A1, 2012 ;
Location in patent: Page/Page column 147-148 ;
WO 2012/030924 A1
