Fmoc-(R)-2-氨基-3-苄氧基丙酸合成路线 （共 3 条）
反应条件
1: toluene-4-sulfonic acid / toluene / 2 h / |Reflux 2: triethylsilane; trifluoroacetic acid / acetonitrile / 2 h / 75 °C / |Flow reactor View Scheme
参考文献
Buba, Annette E.; Koch, Stefan; Kunz, Horst; Loewe, Holger
European Journal of Organic Chemistry, 2013 , # 21 p. 4509 - 4513
反应条件
thionyl chloride; N,N-dimethyl-formamide in dichloromethane 1 h; Ambient temperature;
参考文献
Carpino, Louis A.; Cohen, Beri J.; Stephens, Kenton E.; Sadat-Aalaee, S. Yahya; Tien, Jien-Heh; Langridge, Denton C.
Journal of Organic Chemistry, 1986 , vol. 51, # 19 p. 3732 - 3734
反应条件
1: 100 percent / CH2Cl2; cyclohexane / 40 °C
2: 29 percent / H2; acetic acid / Pd/C / ethanol
View Scheme
参考文献
Ginisty, Maryon; Gravier-Pelletier, Christine; Le Merrer, Yves
Tetrahedron Asymmetry, 2006 , vol. 17, # 1 p. 142 - 150
