1: hydroquinone in N,N-dimethyl-formamide
T=80°C; 2 h;
2: ethyl 2-bromo-2-methyl propionate in N,N-dimethyl-formamide
T=20°C; 3 h;
3: With hydrogenchloride; water
参考文献
Pierre Fabre Medicament
Patent: US2008/167313 A1, 2008 ;
Location in patent: Page/Page column 15-16 ;