1: pyrrolidin-1-yl-2,5-dione With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1 h; Inert atmosphere; 2: pivaloyl chloride in tetrahydrofuran; hexane T=-78 - 20°C; 2.16667 h; Inert atmosphere;
参考文献
Taaning, Rolf H.; Lindsay, Karl B.; Schiott, Birgit; Daasbjerg, Kim; Skrydstrup, Troels
Journal of the American Chemical Society, 2009 , vol. 131, # 29 p. 10253 - 10262
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran T=20°C; Alkylation; Mitsunobu reaction; 24 h;
参考文献
Tarling, Chris A.; Holmes, Andrew B.; Markwell, Roger E.; Pearson, Neil D.
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 12 p. 1695 - 1701
[(PPh3)3Pd] in N,N-dimethyl-formamide T=60°C; 5 h;
参考文献
Inoue, Yoshio; Taguchi, Masaaki; Toyofuku, Masanori; Hashimoto, Harukichi
Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 10 p. 3021 - 3022
[(PPh3)3Pd] in N,N-dimethyl-formamide T=100°C; 5 h;
参考文献
Inoue, Yoshio; Taguchi, Masaaki; Toyofuku, Masanori; Hashimoto, Harukichi
Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 10 p. 3021 - 3022
1: pyrrolidin-1-yl-2,5-dione With potassium hydroxide in ethanol HeatingInert atmosphere; 2: acetyl chloride in benzene 1 h; RefluxInert atmosphere;
参考文献
Taaning, Rolf H.; Lindsay, Karl B.; Schiott, Birgit; Daasbjerg, Kim; Skrydstrup, Troels
Journal of the American Chemical Society, 2009 , vol. 131, # 29 p. 10253 - 10262
