反应条件
1: ethylene glycol; crotonaldehyde With 2,3-dihydroxybutanedioic acid in toluene 12 h; RefluxLarge scale reaction; 2: carbon monoxide With Rh(CO)2(acac); hydrogen; BIPHEPHOS in tetrahydrofuran T=80°C; P=2250.23 Torr; Inert atmosphereLarge scale reaction;
参考文献
Cobley, Christopher J.; Lloyd, Michael C.; Simmonds, Shaun; Hanson, Christopher H.; Peng, Wei Jun
Organic Process Research and Development, 2011 , vol. 15, # 1 p. 284 - 290