四氢吡咯合成路线

参考文献

Abe; Haga; Negi; Morita; Takayanagi; Hamamura
Tetrahedron, 2001 , vol. 57, # 14 p. 2701 - 2710

参考文献

Sengmany, Stephane; Vitu-Thiebaud, Arnaud; Le Gall, Erwan; Condon, Sylvie; Leonel, Eric; Thobie-Gautier, Christine; Pipelier, Muriel; Lebreton, Jacques; Dubreuil, Didier
Journal of Organic Chemistry, 2013 , vol. 78, # 2 p. 370 - 379

123-75-1四氢吡咯+

586-75-44-溴苯甲酰氯

5543-27-14-(吡咯啉基羰基)溴苯

参考文献

Giranda, Vincent L.; Penning, Thomas D.; Gandhi, Virajkamar B.; Thomas, Sheela A.; Zhu, Gui-Dong; Gong, Jianchun
Patent: US2007/259937 A1, 2007 ;
Location in patent: Page/Page column 17 ;

123-75-1四氢吡咯+

1122-91-44-溴苯甲醛

5543-27-14-(吡咯啉基羰基)溴苯

参考文献

Ekoue-Kovi, Kekeli; Wolf, Christian
Organic Letters, 2007 , vol. 9, # 17 p. 3429 - 3432

123-75-1四氢吡咯+

109-96-63-吡咯啉+

24424-99-5二碳酸二叔丁酯

73286-70-1N-Boc-3-吡咯啉+

86953-79-91-Boc-四氢吡咯

参考文献

ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2005/13998 A1, 2005 ;
Location in patent: Page/Page column 66-67 ;
WO 2005/013998 A1

123-75-1四氢吡咯+

109-96-63-吡咯啉+

24424-99-5二碳酸二叔丁酯

73286-70-1N-Boc-3-吡咯啉

参考文献

PFIZER INC.
Patent: EP1134213 A2, 2001 ;

123-75-1四氢吡咯+

625-36-53-氯丙酰氯

63177-38-83-氯-1-(1-吡咯烷基)-1-丙酮

参考文献

Faist, Johanna; Seebacher, Werner; Kaiser, Marcel; Brun, Reto; Saf, Robert; Weis, Robert
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 18 p. 6796 - 6804

123-75-1四氢吡咯+

123-54-6乙酰丙酮+

109-77-3丙二腈

693254-24-94,6-二甲基-2-(吡咯烷-1-基)烟腈

参考文献

Zonouzi, Afsaneh; Izakian, Zakieh; Ng, Seik Weng
Heterocycles, 2012 , vol. 85, # 11 p. 2713 - 2721,9

123-75-1四氢吡咯+

74-96-4溴乙烷

7335-06-0

参考文献

Aitken, David J; Beaufort, Virginie; Chalard, Pierre; Cladiere, Jean-Luc; Dufour, Monique; Pereira, Elisabeth; Thery, Vincent
Tetrahedron, 2002 , vol. 58, # 29 p. 5933 - 5940

123-75-1四氢吡咯+

141-78-6

7335-06-0

参考文献

Segre et al.
Annali di Chimica (Rome, Italy), 1957 , vol. 47, p. 1177,1183