反应条件
1: 1.) (nBu)2BOTf, Et3N, 4.) H2O2 / 1.) -78 deg C, 30 min, 2.) 20 deg C, 2 h, 3.) 0 deg C, 2 h, 4.) MeOH, ether, 0 deg C, 1 h 2: 92 percent / NaN3 / dimethylsulfoxide / 12 h / 25 °C 3: 97 percent / 2,6-lutidine / CH2Cl2 / 2.5 h / 0 °C 4: 81 percent / LiBH4 / tetrahydrofuran / 3 h / 0 °C 5: 90 percent / nBu4NF / tetrahydrofuran / 1 h / 25 °C 6: HS(CH2)3SH, Et3N / methanol / 24 h / 25 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 110, # 23 p. 7910 - 7912
