反应条件
1: TiCl4, PhSH / CH2Cl2 / 2 h / 0 °C 2: K2CO3 / methanol / 2 h / 0 °C 3: Et3N / 4-dimethylaminopyridine / CH2Cl2 / 2 h / 0 °C 4: 84 percent / CuBr / tetrahydrofuran / 4 h / -30 - 0 °C 5: 1.) NaI, Me3SiCl, 2.) POCl3 / 1.) CH3CN, H2O, 0 - 10 deg C, 2 h, 2.) pyridine, CH3CN, 0 - 15 deg C, 4 h 6: 4N HCl / tetrahydrofuran / 24 h / Ambient temperature 7: aq. NaOH / Ambient temperature 8: NaOH / aq. ethanol / 12 h / 95 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 35, # 5 p. 745 - 748
