2-(N-苄基甲酰胺)乙酸甲酯合成路线 （共 5 条）
反应条件
acetic anhydride in water T=100°C; 1 h;
参考文献
Soede-Huijbregts; Van Laren; Hulsbergen; Raap; Lugtenburg
Journal of Labelled Compounds and Radiopharmaceuticals, 2001 , vol. 44, # 12 p. 831 - 841
反应条件
hydrogenchloride und Behandeln des Reaktionsprodukts mit Natriumformiat und Ameisensaeure und anschliessend mit Acetanhydrid;
参考文献
Jones
Journal of the American Chemical Society, 1949 , vol. 71, p. 644,645
反应条件
1: 92 percent / Et3N / tetrahydrofuran / 20 °C 2: 92 percent / Ac2O / H2O / 1 h / 100 °C View Scheme
参考文献
Soede-Huijbregts; Van Laren; Hulsbergen; Raap; Lugtenburg
Journal of Labelled Compounds and Radiopharmaceuticals, 2001 , vol. 44, # 12 p. 831 - 841
反应条件
1.1: 88 percent / MeONa / toluene / 24 h 2.1: 83 percent / aq. HCl / methanol / 20 h / 20 °C 3.1: NaNO2; HNO3 / H2O / 0.17 h 3.2: 98 percent / Na2CO3 / H2O / Heating 4.1: 89 percent / LiAlH4 / tetrahydrofuran View Scheme
参考文献
Soede-Huijbregts; Van Laren; Hulsbergen; Raap; Lugtenburg
Journal of Labelled Compounds and Radiopharmaceuticals, 2001 , vol. 44, # 12 p. 831 - 841
反应条件
1.1: 88 percent / MeONa / toluene / 24 h
2.1: 83 percent / aq. HCl / methanol / 20 h / 20 °C
3.1: NaNO2; HNO3 / H2O / 0.17 h
3.2: 98 percent / Na2CO3 / H2O / Heating
View Scheme
参考文献
Jones
Journal of the American Chemical Society, 1949 , vol. 71, p. 644,645
