1-[(2R,3R,4S,5R)-3,4-二羟基-5-(羟基甲基)四氢呋喃-2-基]吡唑-3,4-二甲酰胺合成路线 （共 2 条）
反应条件
ammonia in methanol T=95°C; 16 h;
参考文献
Sanghvi, Yogesh S.; Bhattacharya, Birendra K.; Kini, Ganesh D.; Matsumoto, Steven S.; Larson, Steven B.; et al.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 1 p. 336 - 344
反应条件
1: trimethylsilyl trifluoromethanesulfonate / acetonitrile / 12 h / Ambient temperature 2: 82 percent / NH3 / methanol / 16 h / 95 °C View Scheme
参考文献
Sanghvi, Yogesh S.; Bhattacharya, Birendra K.; Kini, Ganesh D.; Matsumoto, Steven S.; Larson, Steven B.; et al.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 1 p. 336 - 344
