1-(三异丙基硅基)吲哚合成路线 （共 17 条）
反应条件
1: NBS / tetrahydrofuran; hexane / 2 h / -78 °C 2: tert-BuLi / pentane; tetrahydrofuran / 0.17 h / -78 °C 3: pentane; tetrahydrofuran / 0.25 h / -78 °C 4: TBAF / tetrahydrofuran / 0.17 h / 25 °C View Scheme
参考文献
Amat, Mercedes; Sathyanarayana, Swargam; Hadida, Sabine; Bosch, Joan
Heterocycles, 1996 , vol. 43, # 8 p. 1713 - 1718
反应条件
1: With N,N,N',N,-tetramethylethylenediamine; tert.-butyl lithium in hexane; pentane T=0°C; 3 h; 2: With 1,2-dibromo-1,1,2,2-tetrafluoroethane in diethyl ether T=-78°C; 1 h;
参考文献
Matsuzono, Mai; Fukuda, Tsutomu; Iwao, Masatomo
Tetrahedron Letters, 2001 , vol. 42, # 43 p. 7621 - 7623
反应条件
N-bromosuccinmide in tetrahydrofuran T=-78°C; Yield given. Yields of byproduct given;
参考文献
Hoerrner, R. Scott; Askin, David; Volante, R. P.; Reider, Paul J.
Tetrahedron Letters, 1998 , vol. 39, # 21 p. 3455 - 3458
反应条件
Yield given. Multistep reaction;
参考文献
Beswick; Greenwood; Mowlem; Nechvatal; Widdowson
Tetrahedron, 1988 , vol. 44, # 23 p. 7325 - 7334
反应条件
1: NBS / tetrahydrofuran; hexane / 2 h / -78 °C
2: tert-BuLi / pentane; tetrahydrofuran / 0.17 h / -78 °C
3: pentane; tetrahydrofuran / 0.25 h / -78 °C
4: TBAF / tetrahydrofuran / 0.17 h / 25 °C
View Scheme
参考文献
Amat, Mercedes; Sathyanarayana, Swargam; Hadida, Sabine; Bosch, Joan
Heterocycles, 1996 , vol. 43, # 8 p. 1713 - 1718
反应条件
1: NBS / tetrahydrofuran; hexane / 2 h / -78 °C
2: tert-BuLi / pentane; tetrahydrofuran / 0.17 h / -78 °C
3: pentane; tetrahydrofuran / 0.25 h / -78 °C
4: TBAF / tetrahydrofuran / 0.17 h / 25 °C
View Scheme
参考文献
Amat, Mercedes; Sathyanarayana, Swargam; Hadida, Sabine; Bosch, Joan
Heterocycles, 1996 , vol. 43, # 8 p. 1713 - 1718
反应条件
1: 83 percent / 1/2[IrCl(COD)]2-(4,4'-di-tert-butyl-2,2'-bipyridine) / octane / 16 h / 80 °C
2: TBAF
View Scheme
参考文献
Takagi, Jun; Sato, Kazuaki; Hartwig, John F; Ishiyama, Tatsuo; Miyaura, Norio
Tetrahedron Letters, 2002 , vol. 43, # 32 p. 5649 - 5651
