6-甲氧基-5-(4-甲基咪唑-1-基)吡啶-2-胺合成路线

1232039-16-56-甲氧基-5-(4-甲基咪唑-1-基)吡啶-2-胺

参考文献

ORTHO-MCNEIL-JANSSEN PHARMACEUTICALS, INC; GIJSEN, Henricus, Jacobus, Maria; BISCHOFF, Francois Paul; ZHUANG, Wei; VAN BRANDT, Sven, Franciscus, Anna; SURKYN, Michel; ZAJA, Mirko; BERTHELOT, Didier, Jean-Claude; DE CLEYN, Michel, Anna, Jozef; MACDONALD, Gregor, James; OEHLRICH, Daniel
Patent: WO2010/94647 A1, 2010 ;
Location in patent: Page/Page column 76-77 ;
WO 2010/094647 A1

822-36-64-甲基咪唑+

1211533-83-35-溴-6-甲氧基吡啶-2-胺

1232039-16-56-甲氧基-5-(4-甲基咪唑-1-基)吡啶-2-胺

参考文献

ASTRAZENECA AB
Patent: US2012/122843 A1, 2012 ;
Location in patent: Page/Page column 14-15 ;

89284-11-7

1232039-16-56-甲氧基-5-(4-甲基咪唑-1-基)吡啶-2-胺

参考文献

ASTRAZENECA AB
Patent: US2012/122843 A1, 2012 ;

19798-81-32-氨基-6-溴吡啶

1232039-16-56-甲氧基-5-(4-甲基咪唑-1-基)吡啶-2-胺

参考文献

ASTRAZENECA AB
Patent: US2012/122843 A1, 2012 ;

39856-57-02,6-二溴-3-氨基吡啶

1232039-16-56-甲氧基-5-(4-甲基咪唑-1-基)吡啶-2-胺

参考文献

Bischoff, Francois; Berthelot, Didier; De Cleyn, Michel; MacDonald, Gregor; Minne, Garrett; Oehlrich, Daniel; Pieters, Serge; Surkyn, Michel; Trabanco, Andres A.; Tresadern, Gary; Van Brandt, Sven; Velter, Ingrid; Zaja, Mirko; Borghys, Herman; Masungi, Chantal; Mercken, Marc; Gijsen, Harrie J. M.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 21 p. 9089 - 9106,18

89466-18-22-甲氧基-3-氨基-6-溴吡啶

1232039-16-56-甲氧基-5-(4-甲基咪唑-1-基)吡啶-2-胺

参考文献

Bischoff, Francois; Berthelot, Didier; De Cleyn, Michel; MacDonald, Gregor; Minne, Garrett; Oehlrich, Daniel; Pieters, Serge; Surkyn, Michel; Trabanco, Andres A.; Tresadern, Gary; Van Brandt, Sven; Velter, Ingrid; Zaja, Mirko; Borghys, Herman; Masungi, Chantal; Mercken, Marc; Gijsen, Harrie J. M.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 21 p. 9089 - 9106,18