反应条件
1: ethyl 6-methyl-2-oxo-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate With caesium carbonate in N,N-dimethyl-formamide
T=20°C; 1 h;
2: methyl iodide in N,N-dimethyl-formamide
T=20°C; 17 h; regioselective reaction;
参考文献
Putatunda, Salil; Chakraborty, Srabasti; Ghosh, Swatilekha; Nandi, Pinki; Chakraborty, Supriya; Sen, Parimal C.; Chakraborty, Arijit
European Journal of Medicinal Chemistry, 2012 , vol. 54, p. 223 - 231
