1.1: N-iodo-succinimide; [bis(acetoxy)iodo]benzene; palladium diacetate / 1,2-dichloro-ethane / 1 h / 70 °C / Inert atmosphere 2.1: boron trichloride / n-heptane; dichloromethane / 0 - 20 °C / Inert atmosphere 2.2: 20 °C / Inert atmosphere View Scheme

1: silver(I) acetate; palladium diacetate / 1,2-dichloro-ethane / 5 h / 80 °C / Inert atmosphere 2: silver fluoride / methanol / 20 °C / Inert atmosphere; Darkness View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1.1: n-butyllithium / hexanes; diethyl ether / 0.67 h / -78 &deg;C / Inert atmosphere<br />1.2: -78 - 20 &deg;C / Inert atmosphere<br />2.1: n-butyllithium / tetrahydrofuran; hexanes / -78 &deg;C / Inert atmosphere<br />2.2: -78 - 30 &deg;C / Inert atmosphere<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1.1: n-butyllithium / hexanes; diethyl ether / 0.67 h / -78 &deg;C / Inert atmosphere<br />1.2: -78 - 20 &deg;C / Inert atmosphere<br />2.1: n-butyllithium / tetrahydrofuran; hexanes / -78 &deg;C / Inert atmosphere<br />2.2: -78 - 30 &deg;C / Inert atmosphere<br /> <br /> &nbsp;