(8S,9S,10R,13R,14S,17S)-17-乙酰基-13-(1,3-二噻戊环-2-基甲基)-10-甲基-1,2,6,7,8,9,11,12,14,15,16,17-十二氢环戊烯并[a]菲-3-酮合成路线 （共 2 条）
→
123376-04-5(8S,9S,10R,13R,14S,17S)-17-乙酰基-13-(1,3-二噻戊环-2-基甲基)-10-甲基-1,2,6,7,8,9,11,12,14,15,16,17-十二氢环戊烯并[a]菲-3-酮
反应条件
N-methylpiperidin-2-one; aluminum isopropoxide in toluene 3 h; Heating;
参考文献
Perard, Serge; Viger, Antoinette; Marquet, Andree
Steroids, 1990 , vol. 55, # 6 p. 271 - 275
→
123376-04-5(8S,9S,10R,13R,14S,17S)-17-乙酰基-13-(1,3-二噻戊环-2-基甲基)-10-甲基-1,2,6,7,8,9,11,12,14,15,16,17-十二氢环戊烯并[a]菲-3-酮
反应条件
1: 61 percent / BF3*Et2O / CH2Cl2 / 3 h / -10 °C 2: 59 percent / N-methylpiperidone, aluminium isopropoxide / toluene / 3 h / Heating View Scheme
参考文献
Perard, Serge; Viger, Antoinette; Marquet, Andree
Steroids, 1990 , vol. 55, # 6 p. 271 - 275
