N-叔丁氧羰基-六亚甲基亚胺合成路线 （共 4 条）
反应条件
N,N,N',N,-tetramethylethylenediamine; sec.-butyllithium Yield given. Multistep reaction;
参考文献
Beak, Peter; Lee, Won Koo
Journal of Organic Chemistry, 1993 , vol. 58, # 5 p. 1109 - 1117
反应条件
[H2-cryptand 222](Br3)2 in acetonitrile
T=20°C; 0.25 h; chemoselective reaction;
参考文献
Zolfigol, Mohammad Ali; Moosavi-Zare, Ahmad Reza; Moosavi, Parvin; Khakyzadeh, Vahid; Zare, Abdolkarim
Comptes Rendus Chimie, 2013 , vol. 16, # 11 p. 962 - 966
参考文献
Pandey, Ganesh; Laha, Joydev K; Lakshmaiah
Tetrahedron, 2002 , vol. 58, # 18 p. 3525 - 3534
反应条件
1: N-Boc-azepine With N,N,N',N,-tetramethylethylenediamine; sec.-butyllithium in diethyl ether; hexane
T=-78°C; 3 h;
2: With C13H28N2O; sec.-butyllithium in diethyl ether; hexane
T=-78 - -30°C;
3: carbon dioxide in diethyl ether; hexane
T=-78 - 20°C; 18 h; optical yield given as percent eeenantioselective reaction;
参考文献
Coldham, Iain; Raimbault, Sophie; Whittaker, David T. E.; Chovatia, Praful T.; Leonori, Daniele; Patel, Jignesh J.; Sheikh, Nadeem S.
Chemistry - A European Journal, 2010 , vol. 16, # 13 p. 4082 - 4090
