N-苄氧羰基-L-精氨酸合成路线 （共 20 条）
反应条件
2: H2 / Pd black 4: TFA, 5percent thioanisole / 50 °C View Scheme
参考文献
Maurs, Michele; Acher, Francine; Azerad, Robert
Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 84, p. 22 - 26
反应条件
COBALT; urethane hydrolase II T=33°C; 2 h; phosphate buffer pH 6.5; Product distributionKinetics;
参考文献
Matsamura, Eiko; Yamamoto, Eiko; Kawano, Tatsu; Shin, Takashi; Murao, Sawao
Agricultural and Biological Chemistry, 1986 , vol. 50, # 6 p. 1563 - 1572
反应条件
sodium hydroxide 1.) acetone, 3 h, 2.) ethyl acetate; Yield given. Multistep reaction;
参考文献
Fujino, Masahiko; Wakimasu, Mitsuhiro; Kitada, Chieko
Chemical & Pharmaceutical Bulletin, 1981 , vol. 29, # 10 p. 2825 - 2831
反应条件
1: (S)-N2-(benzyloxycarbonyl)-arginine With chloro-trimethyl-silane; N-ethyl-N,N-diisopropylamine 2: benzyl chloroformate
参考文献
Formanovsky; Popova; Mikhura
Russian Journal of Bioorganic Chemistry, 2009 , vol. 35, # 6 p. 752 - 758
反应条件
1: diisopropylethylamine (DiPEA) / 1,2-dichloro-ethane / 1.) RT, 30 min; 2.) 40-50 deg C 2: diisopropylethylamine (DiPEA) / 1,2-dichloro-ethane / Ambient temperature View Scheme
参考文献
Moynihan, Humphrey A.; Yu, Weiping
Tetrahedron Letters, 1998 , vol. 39, # 20 p. 3349 - 3352
参考文献
Matsamura, Eiko; Yamamoto, Eiko; Kawano, Tatsu; Shin, Takashi; Murao, Sawao
Agricultural and Biological Chemistry, 1986 , vol. 50, # 6 p. 1563 - 1572
反应条件
(i) PBr3, (ii) /BRN= 1721722/; Multistep reaction;
参考文献
Hirschmann; Schwam; Strachan; Schoenewaldt; Barkemeyer; Miller; Conn; Garsky; Veber; Denkewalter
Journal of the American Chemical Society, 1971 , vol. 93, # 11 p. 2746 - 2754
反应条件
pyridine; trichlorophosphate
0.5 h;
参考文献
Rijkers, D. T. S.; Hemker, H. C.; Nefkens, G. H. L.; Tesser, G. I.
Recueil des Travaux Chimiques des Pays-Bas, 1991 , vol. 110, # 7-8 p. 347 - 348
反应条件
Nα-benzyloxycarbonyl amino acid urethane hydrolase II; COBALT
T=33°C; 0.5 h; pH=6.5; Rate constant;
参考文献
Matsumura, Eiko; Shin, Takashi; Murao, Sawao; Yamamoto, Eiko; Kawano, Tatsu
Chemical & Pharmaceutical Bulletin, 1985 , vol. 33, # 1 p. 408 - 411
反应条件
2: hydrogen bromide / acetic acid
4: H2 / catalytic hydrog.
View Scheme
参考文献
Nikolaev, S. V.; Martinov, V. F.
Chemistry of Natural Compounds, 1985 , vol. 21, # 2 p. 269 - 270
Khimiya Prirodnykh Soedinenii, 1985 , # 2 p. 281 - 282
