1: 58 percent / diphenyl ether / 5 h / 240 °C 2: 99 percent / 35percent HCl / ethanol / 2 h / Ambient temperature 3: 47 percent / K2CO3, KI / dimethylformamide / 0.5 h / 105 - 110 °C 4: 84 percent / dimethylformamide / Ambient temperature 5: 88 percent / KOH / 2-methyl-propan-2-ol; H2O / 1 h / 50 - 60 °C 6: 62 percent / KHCO3 / dimethylformamide / 5 h / Ambient temperature View Scheme

N-ethyl-N,N-diisopropylamine; sodium bromide 1.) DMF, 303 K, 2 h, 2.) DMF, 304 K, 1 h; Yield given. Multistep reaction;

potassium hydrogencarbonate in N,N-dimethyl-formamide T=30°C; 2 h; various periods of time (3 h); activation energy 29.1 kJ mol-1; Product distributionRate constant;

potassium hydrogencarbonate 3 h; also in presence of DIPEA, car. concn. of substrates; Product distribution;