(S)-2-(N-BOC-哌啶-3-基)-1H-苯并咪唑合成路线 （共 3 条）
反应条件
acetic acid T=65°C; 2 h; Inert atmosphere;
参考文献
Takeda Pharmaceutical Company Limited
Patent: US8138168 B1, 2012 ;
Location in patent: Page/Page column 228 ;
US 8138168 B1
反应条件
1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; 4-methyl-morpholine / N,N-dimethyl-formamide / 16 h / 20 °C / Inert atmosphere 2: acetic acid / 2 h / 65 °C / Inert atmosphere View Scheme
参考文献
Takeda Pharmaceutical Company Limited
Patent: US8138168 B1, 2012 ;
US 8138168 B1
反应条件
1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; 4-methyl-morpholine / N,N-dimethyl-formamide / 16 h / 20 °C / Inert atmosphere 2: acetic acid / 2 h / 65 °C / Inert atmosphere View Scheme
参考文献
Takeda Pharmaceutical Company Limited
Patent: US8138168 B1, 2012 ;
US 8138168 B1
