N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane Reflux;

1.1: potassium carbonate / dimethyl sulfoxide / 72 h / 20 °C 2.1: sodium hydroxide; water / tetrahydrofuran; methanol 3.1: oxalyl dichloride / N,N-dimethyl-formamide / tetrahydrofuran / 0 - 20 °C 3.2: -78 - 20 °C 4.1: N-bromosuccinmide / tetrachloromethane / Reflux View Scheme

1.1: sodium hydroxide; water / tetrahydrofuran; methanol 2.1: oxalyl dichloride / N,N-dimethyl-formamide / tetrahydrofuran / 0 - 20 °C 2.2: -78 - 20 °C 3.1: N-bromosuccinmide / tetrachloromethane / Reflux View Scheme

1.1: oxalyl dichloride / N,N-dimethyl-formamide / tetrahydrofuran / 0 - 20 °C 1.2: -78 - 20 °C 2.1: N-bromosuccinmide / tetrachloromethane / Reflux View Scheme