2-(1-萘甲酰基)丙二腈合成路线 （共 4 条）
反应条件
sodium hydride in tetrahydrofuran; paraffin oil (nujol) T=5 - 10°C; 3 h;
参考文献
WO2011/94628 A1, ;
Page/Page column 104 ;
WO 2011/094628 A1
反应条件
1: oxalyl dichloride / N,N-dimethyl-formamide; hexane / 1 h / 20 °C 2: sodium hydride / tetrahydrofuran / 1 h / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 56, # 7 p. 3068 - 3077
反应条件
sodium hydrogencarbonate in 1,4-dioxane; water 1 h; Reflux;
参考文献
Lourido, Sebastian; Zhang, Chao; Lopez, Michael S.; Tang, Keliang; Barks, Jennifer; Wang, Qiuling; Wildman, Scott A.; Shokat, Kevan M.; Sibley, L. David
Journal of Medicinal Chemistry, 2013 , vol. 56, # 7 p. 3068 - 3077
反应条件
1: sodium hydrogencarbonate / water; 1,4-dioxane / 1 h / |Reflux 2: ethanol / 1 h / |Reflux View Scheme
参考文献
Lourido, Sebastian; Zhang, Chao; Lopez, Michael S.; Tang, Keliang; Barks, Jennifer; Wang, Qiuling; Wildman, Scott A.; Shokat, Kevan M.; Sibley, L. David
Journal of Medicinal Chemistry, 2013 , vol. 56, # 7 p. 3068 - 3077
