反应条件
1: 2,6-dimethylbenzeneamine With ethyl bromide; iodine; magnesium in tetrahydrofuran T=40 - 60°C; 2: propyl (1-propylpiperidine)-2-carboxylate in tetrahydrofuran T=40 - 70°C; 3: With hydrogenchloride in water; ethyl acetate T=5 - 15°C;
参考文献
JUBILANT ORGANOSYS LIMITED; THANKI, Bhavin, Prabhudas; SINGH, Harinder; SINGH, Anand, Kumar; SINGH, Khushwant; DUBEY, Sushil, Kumar
Patent: WO2010/84516 A1, 2010 ;
Location in patent: Page/Page column 7 ;