N-[5-[(3-氨基-3-亚氨基丙基)氨基甲酰]-1-甲基吡咯-3-基]-2-甲酰氨基-4-甲基-1,3-噻唑-5-甲酰胺盐酸盐合成路线 (共 5 条)
反应条件
1: hydrogen / 10percent Pd on charcoal / methanol / 760 Torr / Ambient temperature 2: dicyclohexylcarbodiimid / dimethylformamide / Ambient temperature View Scheme
参考文献
Rao; Bathini; Lown
Journal of Organic Chemistry, 1990 , vol. 55, # 2 p. 728 - 737
反应条件
1: hydrogen / 760 Torr 2: hydrogen / 10percent Pd on charcoal / methanol / 760 Torr / Ambient temperature 3: dicyclohexylcarbodiimid / dimethylformamide / Ambient temperature View Scheme
参考文献
Rao; Bathini; Lown
Journal of Organic Chemistry, 1990 , vol. 55, # 2 p. 728 - 737
反应条件
1: 47 percent / acetic anhydride / 18 h / Ambient temperature 2: dicyclohexylcarbodiimid / dimethylformamide / Ambient temperature View Scheme
参考文献
Rao; Bathini; Lown
Journal of Organic Chemistry, 1990 , vol. 55, # 2 p. 728 - 737
反应条件
1: 85 percent / 0.5 M ethanolic sodium hydroxide / 24 h / Ambient temperature 2: 47 percent / acetic anhydride / 18 h / Ambient temperature 3: dicyclohexylcarbodiimid / dimethylformamide / Ambient temperature View Scheme
参考文献
Rao; Bathini; Lown
Journal of Organic Chemistry, 1990 , vol. 55, # 2 p. 728 - 737
反应条件
dicyclohexyl-carbodiimide in N,N-dimethyl-formamide Ambient temperature; Yield given;
参考文献
Rao; Bathini; Lown
Journal of Organic Chemistry, 1990 , vol. 55, # 2 p. 728 - 737