1: dimethylformamide / Ambient temperature 2: H2O2, NaWO4 / methanol 3: 99 percent / CF3CO2H / CH2Cl2 4: 70 percent / DPPA, Et3N View Scheme

<b>Multi-step reaction with 3 steps<br /> </b>1: 1) 30percent H₂O₂, LiOH*H₂O, 2) Pd black, cyclohexene, EtOH / 1) 3:1 THF-water, r.t., 6.5h, 2) reflux, 4h<br />2: 90 percent / DCC-HOBT / dimethylformamide<br />3: 94 percent / pyridine<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 90 percent / DCC-HOBT / dimethylformamide<br />2: 94 percent / pyridine<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 1) KOH, 2) HOBT, DCC, NEt₃ <br />2: 33 percent / NaBH₄ / ethanol<br />3: pyridine<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '103233', constants.ctx, '0')">pyridine</a> <br /> <br /> &nbsp;