(R)-2-苄基-3-羟基丙酸合成路线 （共 15 条）
反应条件
water; sodium hydroxide in methanol
参考文献
Choi, Seung-Su; Ji, Ae-Ri; Yu, Seung-Woo; Cho, Bong-Hwan; Park, Jung Dae; Park, Jun Hyoung; Lee, Hyun Soo; Ryu, Seong Eon; Kim, Dong Han; Kang, Jae-Hoon; Lee, Seung-Taek
Bulletin of the Korean Chemical Society, 2011 , vol. 32, # 6 p. 2032 - 2038
反应条件
1: 90 percent / methanol; K2CO3; water / 2 h / 20 °C
2: 86 percent / acetyl chloride / 24 h / 20 °C
3: phosphate buffer; α-chymotrypsin; sodium hydroxide / 18 h / pH 7.5 / Enzymatic reaction
View Scheme
参考文献
Kim, Dong H.; Park, Jeong-il; Chung, Sang J.; Park, Jung Dae; Park, No-Kyung; Han, Jong Hoon
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 8 p. 2553 - 2560
反应条件
1: With sodium hydroxide; phosphate buffer; α-chymotrypsin
pH=7.5; 18 h; Enzymatic reaction;
2: With sodium hydroxide; α-chymotrypsin
参考文献
Kim, Dong H.; Park, Jeong-il; Chung, Sang J.; Park, Jung Dae; Park, No-Kyung; Han, Jong Hoon
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 8 p. 2553 - 2560
反应条件
Tris buffer; α-chymotrypsin in dimethyl sulfoxide
pH=7.5; Enzyme kinetics;
参考文献
Kim, Dong H.; Park, Jeong-il; Chung, Sang J.; Park, Jung Dae; Park, No-Kyung; Han, Jong Hoon
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 8 p. 2553 - 2560
反应条件
1: NaOH, H2O, EDCI / tetrahydrofuran / Ambient temperature
2: DEAD, Ph3P / tetrahydrofuran / Ambient temperature
3: 100 percent / LiOH, H2O / tetrahydrofuran; methanol / 0 °C
4: H2 / 10percent Pd/C / methanol
View Scheme
参考文献
Jin, Yonghao; Kim, Dong H.
Synlett, 1998 , # 11 p. 1189 - 1190
