反应条件
1: 1.) N,N-diisopropylethylamine / 1.) acetonitrile, reflux, 22 h, 2.) dichloromethane, room temperature, 2 h
2: 89 percent / HCl(gas) / CH2Cl2; methanol / 6 - 20 °C
3: 80 percent / pyridine / 21 h / 82 °C
View Scheme
参考文献
Beylin; Colbry; Goel; Haky; Johnson; Kanter; Leeds; Leja; Lewis; Rithner; Showalter; Sercel; Turner; Uhlendorf
Journal of Heterocyclic Chemistry, 1989 , vol. 26, # 1 p. 85 - 96
