sulfuric acid in water; acetic acid 48 h; Heating;

potassium hydroxide; ethanol in water 25 h; Heating;

1: 61 percent / bromine / CHCl3 / 0.01 h 2: 1-methyl-2-pyrrolidinone / 2 h / 180 °C 3: sodium hydroxide / H2O / 60 h 4: 64 percent / ethanol, potassium hidroxide / H2O / 25 h / Heating View Scheme

1: 1-methyl-2-pyrrolidinone / 2 h / 180 °C 2: sodium hydroxide / H2O / 60 h 3: 64 percent / ethanol, potassium hidroxide / H2O / 25 h / Heating View Scheme

1: sodium hydroxide / H2O / 60 h 2: 64 percent / ethanol, potassium hidroxide / H2O / 25 h / Heating View Scheme

1: 99 percent / n-butyllithium / hexane; tetrahydrofuran / 2.5 h / -78 °C 2: oxalyl chloride, DMF / benzene / Ambient temperature 3: 81 percent / 35percent ammonia / bis-(2-methoxy-ethyl) ether / Ambient temperature 4: 95 percent / thionyl chloride / dimethylformamide / Ambient temperature 5: 94 percent / aluminum chloride, sodium chloride / hexane; tetrahydrofuran / 1 h / 180 °C 6: 90 percent / cc. sulphuric acid / H2O; acetic acid / 48 h / Heating View Scheme

1: 94 percent / aluminum chloride, sodium chloride / hexane; tetrahydrofuran / 1 h / 180 °C 2: 90 percent / cc. sulphuric acid / H2O; acetic acid / 48 h / Heating View Scheme

1: 95 percent / thionyl chloride / dimethylformamide / Ambient temperature 2: 94 percent / aluminum chloride, sodium chloride / hexane; tetrahydrofuran / 1 h / 180 °C 3: 90 percent / cc. sulphuric acid / H2O; acetic acid / 48 h / Heating View Scheme

1: oxalyl chloride, DMF / benzene / Ambient temperature 2: 81 percent / 35percent ammonia / bis-(2-methoxy-ethyl) ether / Ambient temperature 3: 95 percent / thionyl chloride / dimethylformamide / Ambient temperature 4: 94 percent / aluminum chloride, sodium chloride / hexane; tetrahydrofuran / 1 h / 180 °C 5: 90 percent / cc. sulphuric acid / H2O; acetic acid / 48 h / Heating View Scheme

1: 81 percent / 35percent ammonia / bis-(2-methoxy-ethyl) ether / Ambient temperature 2: 95 percent / thionyl chloride / dimethylformamide / Ambient temperature 3: 94 percent / aluminum chloride, sodium chloride / hexane; tetrahydrofuran / 1 h / 180 °C 4: 90 percent / cc. sulphuric acid / H2O; acetic acid / 48 h / Heating View Scheme