aluminium trichloride; sodium chloride in tetrahydrofuran; hexane T=180°C; 1 h;

1: 99 percent / n-butyllithium / hexane; tetrahydrofuran / 2.5 h / -78 °C 2: oxalyl chloride, DMF / benzene / Ambient temperature 3: 81 percent / 35percent ammonia / bis-(2-methoxy-ethyl) ether / Ambient temperature 4: 95 percent / thionyl chloride / dimethylformamide / Ambient temperature 5: 94 percent / aluminum chloride, sodium chloride / hexane; tetrahydrofuran / 1 h / 180 °C View Scheme

1: 95 percent / thionyl chloride / dimethylformamide / Ambient temperature 2: 94 percent / aluminum chloride, sodium chloride / hexane; tetrahydrofuran / 1 h / 180 °C View Scheme

1: oxalyl chloride, DMF / benzene / Ambient temperature 2: 81 percent / 35percent ammonia / bis-(2-methoxy-ethyl) ether / Ambient temperature 3: 95 percent / thionyl chloride / dimethylformamide / Ambient temperature 4: 94 percent / aluminum chloride, sodium chloride / hexane; tetrahydrofuran / 1 h / 180 °C View Scheme

1: 81 percent / 35percent ammonia / bis-(2-methoxy-ethyl) ether / Ambient temperature 2: 95 percent / thionyl chloride / dimethylformamide / Ambient temperature 3: 94 percent / aluminum chloride, sodium chloride / hexane; tetrahydrofuran / 1 h / 180 °C View Scheme

sulfuric acid in water; acetic acid 48 h; Heating;